As we continue to use antibiotics, many
bacteria develop resistance to them. Since these germs reproduce in
hours, much of this is driven by evolutionary pressure. But how do these
genes form in the first place?
Researchers discovered that nearly 3000 different antibiotic-resistance
genes representing all major resistance mechanisms were detected in
bacteria from grassland and agricultural soil, which have never infected
humans or animals or have been exposed to antibiotics.
Although most of these genes were inactive, they seem to be present in
many different organisms. The researchers do not know why this occurs,
but, since most antibiotics have developed from natural sources such as
fungus (e.g. penicillin) it makes sense that the germs have evolved
these mechanisms.
Next time your doctor tells you that he or
she prefers not to give you antibiotics for a minor infection, you can
understand that we are trying to prevent evolution of
super-bugs.
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